The organic chemistry of drug design and drug action by Richard B. Silverman

The organic chemistry of drug design and drug action



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The organic chemistry of drug design and drug action Richard B. Silverman ebook
Publisher: Academic Press
ISBN: 0126437327, 9780126437324
Format: pdf
Page: 646


The state-of-the-art use of chemical similarity, protein structure, protein-protein interaction, signaling, genetic interaction and metabolic networks in the discovery of drug targets is summarized. We give a comprehensive assessment of the analytical tools of network topology and dynamics. Purcell Strategies of Drug Design. It is contrasted by a reductionist approach , . This book is ideally suited as an advanced text for courses in drug metabolism for students of medicine, pharmacy, pharmacology, biochemistry; and for courses in drug design and drug delivery for students of medicinal chemistry. This led us to the family of cytotoxic chemotherapy drugs designed to kill rapidly growing cells such as those in a cancer tumour. It is time that the actions of the Food and Drug Administration (FDA) speak for themselves and Americans began to question their own absorbent use and blind-loyalty to FDA approved drugs. EUREKAMOMENTS IN ORGANIC CHEMISTRY. The term is loosely used in science to refer to a inter-disciplinary field of study that relies on biology, mathematics, statistics, chemistry, and bioinformatics to describe the dynamic interplay life's elements. Chemistry of Drug Design and drug Action. The organic chemistry of drug design and drug action - Google Books This book represents a new approach based on physical organic chemical principles. This is a one-drug, one-protein model. Korolkovas Essentials of Medicinal Chemistry. Chemistry of Drugs book download Download Chemistry of Drugs The Organic Chemistry of Drug Design and Drug Action, Second. Network description and analysis not only give a systems-level understanding of drug action and disease complexity, but can also help to improve the efficiency of drug design. About the author: Shane holds a Master's degree in organic chemistry and has first-hand industry experience with drug research, design and synthesis. This is a new approach to the teaching of medicinal chemistry. The task in targeted therapy was to identify a key protein that is overactive, overproduced, or somehow altered in cancer cells, and then design a drug that will bind to that protein and inhibit its action. His web site exposes the shocking and sometimes-frightening truth behind FDA approved drugs, sports supplements, and natural medicine. Berger's Medicinal Chemistry and Drug Design.